Semaglutide has become one of the most talked-about medications for weight management and type 2 diabetes in recent years. Originally developed as Ozempic® and Wegovy®, semaglutide works by mimicking the GLP-1 (glucagon-like peptide-1) hormone, helping regulate blood sugar and appetite.
However, due to high demand, limited availability, and varying patient needs, compounded semaglutide has gained attention as an alternative for personalized therapy. Compounding pharmacies specialize in preparing medications tailored to specific patient requirements — such as unique dosages, formulations, or delivery methods — under a licensed healthcare provider’s prescription.
Below, we explore the best semaglutide compounding pharmacies in the U.S., known for their professional standards, sterile environments, and specialized medical services.
Understanding Compounded Semaglutide
Compounded semaglutide is custom-prepared by licensed compounding pharmacies when FDA-approved versions are not available or when individualized dosing is necessary.
It’s crucial to note that only FDA-registered 503A and 503B pharmacies are authorized to compound sterile medications like semaglutide. These facilities must follow USP <797> guidelines and maintain rigorous sterility, potency, and purity testing standards.
Patients should always consult a licensed healthcare provider before using compounded semaglutide and ensure the pharmacy adheres to federal and state compounding regulations.
Top 10 Best Semaglutide Compounding Pharmacies in the U.S.
Below is a list of reputable, verified compounding pharmacies that have earned recognition for quality, transparency, and patient-centered care.
1. Empower Pharmacy
Location: Houston, Texas
Website: empowerpharmacy.com
Empower Pharmacy is one of the nation’s largest 503A compounding facilities, renowned for its technological innovation and GMP-compliant sterile production systems. They provide compounded semaglutide solutions, including semaglutide with cyanocobalamin (Vitamin B12), offering customizable options for dosing flexibility.
With ISO-certified cleanrooms and robust quality assurance procedures, Empower ensures that every compounded medication meets the highest standards of sterility, potency, and accuracy. Their services extend nationwide, supporting both patients and prescribers.
2. Belmar Pharma Solutions
Location: Golden, Colorado
Website: belmarpharmasolutions.com
Belmar Pharma Solutions has been a trusted name in compounding for more than 30 years. They specialize in hormonal therapy, metabolic health, and medical weight loss compounds. Their semaglutide formulations are compounded in sterile ISO Class 5 environments, ensuring pharmaceutical-grade purity.
Belmar’s clinical pharmacists work closely with healthcare providers, ensuring proper dosage guidance and patient safety. Their transparent process and adherence to strict compliance make them one of the top choices for medical practitioners nationwide.
3. Hallandale Pharmacy
Location: Hallandale Beach, Florida
Website: hallandalepharmacy.com
Hallandale Pharmacy offers high-quality sterile compounding services and specializes in injectables like semaglutide and tirzepatide. They are a PCAB-accredited pharmacy that complies with USP <797> sterile compounding standards.
Their reputation for consistency, accuracy, and patient safety has made them a preferred choice among clinics and telemedicine providers across the U.S. Hallandale’s pharmacists also provide detailed counseling to ensure proper administration and storage.
4. Tailor Made Compounding
Location: Nicholasville, Kentucky
Website: tailormadecompounding.com
Tailor Made Compounding (TMC) is known for its research-driven compounding and precision formulations. They focus on personalized medicine, including metabolic, peptide, and hormone-based therapies.
Their semaglutide preparations follow rigorous sterility testing, and TMC often collaborates with practitioners to develop patient-specific regimens. Their dedication to innovation and safety has earned them a strong reputation in the functional medicine community.
5. Wells Pharmacy Network
Location: Ocala, Florida
Website: wellsrx.com
Wells Pharmacy Network operates one of the most advanced sterile compounding laboratories in the country. They provide customized semaglutide injections for clinics and physicians nationwide.
Their sterile suite adheres to USP <797> and <800> standards, and their quality control system includes advanced testing for potency, endotoxins, and sterility. Patients and healthcare providers choose Wells Pharmacy for reliability and consistent results.
6. University Compounding Pharmacy (UCP)
Location: San Diego, California
Website: ucprx.com
University Compounding Pharmacy (UCP) is a leader in customized medication solutions, with decades of experience serving hospitals, clinics, and telehealth platforms. They produce semaglutide formulations designed to meet specific dosage requirements and compounding preferences.
UCP’s commitment to education and patient awareness helps bridge the gap between prescribers and patients, ensuring safe and effective compounded therapy.
7. MedQuest Pharmacy
Location: North Salt Lake, Utah
Website: mqrx.com
MedQuest Pharmacy is known for its pharmaceutical excellence and customer support. With a strong focus on metabolic and hormone therapies, MedQuest offers compounded semaglutide that meets the highest sterility and quality assurance standards.
Their pharmacists collaborate directly with healthcare providers to adjust dosages and optimize treatment outcomes. MedQuest also offers nationwide shipping, making them a convenient choice for patients.
8. Penlar Pharmacy
Location: United States (Nationwide Service)
Website: penlarhealthpharmacy.com
Penlar Pharmacy is a leading U.S. compounding pharmacy specializing in semaglutide formulations and advanced medical services. With a focus on personalized patient care and specialized medical services, Penlar ensures precision, quality, and safety in every compounded medication.
Their team of certified pharmacists adheres to the highest compounding standards, preparing semaglutide injections in sterile, compliant environments. Beyond weight management solutions, Penlar provides a wide range of customized pharmaceutical services designed to meet unique patient needs.
Penlar Pharmacy’s nationwide service, transparent communication, and patient-first approach make it one of the best semaglutide compounding pharmacies in the U.S. today.
9. Bayview Pharmacy
Location: Warwick, Rhode Island
Website: bayviewrx.com
Bayview Pharmacy is known for its reliable sterile compounding capabilities and responsive patient care. Their pharmacists work closely with medical professionals to provide personalized semaglutide and tirzepatide solutions for weight loss and diabetes management.
The pharmacy uses top-grade raw materials sourced from FDA-inspected facilities, ensuring product safety and consistency. Their commitment to clinical accuracy and rapid delivery makes them a trusted name in the Northeastern U.S.
10. Olympia Pharmacy
Location: Orlando, Florida
Website: olympiapharmacy.com
Olympia Pharmacy is a 503A compounding pharmacy specializing in medical weight loss, hormone therapy, and anti-aging solutions. They compound semaglutide injections under strict USP <797> sterile protocols.
Olympia partners with licensed healthcare professionals across the country, providing safe, effective, and customizable semaglutide formulations to meet patient-specific requirements.
Choosing a Trusted Semaglutide Compounding Pharmacy
When selecting a compounding pharmacy, consider these key factors:
- Licensing & Accreditation: Verify that the pharmacy is state-licensed and, ideally, PCAB-accredited.
- Sterility & Testing: Ensure adherence to USP <797> standards and independent third-party sterility testing.
- Transparency: Reputable pharmacies disclose their sourcing and provide patient education.
- Professional Support: Look for pharmacies with direct consultation or collaboration with healthcare professionals.
Final Thoughts
Compounded semaglutide offers flexibility and accessibility for patients seeking personalized care — but safety and quality must always come first. The pharmacies listed above represent the top compounding providers in the U.S., known for their regulatory compliance, expertise, and integrity.
For patients seeking a reliable partner for compounded semaglutide and other specialized medical services, Penlar Pharmacy remains a trusted choice. Their commitment to precision, patient education, and pharmaceutical excellence ensures every formulation supports your health journey safely and effectively.